Precision medicine

October 17, 2024

Amended Trial: Robert Ferris Gives an Update on the EA3132 Trial for Patients With Head and Neck Cancer

The changes aim to alleviate scheduling difficulties during the randomization step, and they introduce the new tumor test for this phase 2 trial testing radiotherapy with or without chemotherapy
May 1, 2024

NCCN Recommends Universal Testing for Microsatellite Instability by PCR/NGS or Mismatch Repair by IHC for All Newly Diagnosed Gastric Cancer Patients

EA2212 is a randomized phase 2 study assessing if chemotherapy plus immunotherapy is superior to immunotherapy alone for patients with operable MSI-H/dMMR gastric and/or gastroesophageal junction cancer
October 19, 2023

It’s a MATCH: Peter O’Dwyer on the Future of Precision Oncology

Following the recent Nature Medicine publication of lessons from the NCI-MATCH trial, two new podcasts discuss the pitfalls and promises of precision oncology—and opportunities to guide the field as it moves forward
April 19, 2023

Now Enrolling: ECOG-ACRIN Opens the ComboMATCH Patient Registration Trial as the Gateway to a Coordinated Set of Treatment Trials

ComboMATCH researchers are discovering new drug combinations that show promise for patients with advanced cancers, based on strong pre-clinical in vivo evidence of therapeutic effectiveness
December 20, 2022

Trial Spotlight: Robert Ferris and Christine Chung on the EA3132 Trial for Patients With Head and Neck Cancer

This phase 2 study is examining whether the addition of cisplatin to PORT will provide a survival benefit to certain patients with stage 3/4 squamous cell carcinoma of the head and neck
April 15, 2022

Trial Spotlight: Nadine Tung on the EA1181/CompassHER2 pCR Trial for HER2-Positive Breast Cancer

This study aims to determine if it is safe to omit adjuvant chemotherapy after surgery for patients with pathologic complete response (pCR) after 12 weeks of pre-operative treatment